Tag Archives: doctor

Brad Pitt, Disney Team Up For Biopic “Dr.Q” About Mexican Immigrant Turned Neurosurgeon

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Brad Pitt, Alfredo Quiñones-Hinojosa and Matthew Lopez
[Andrew Toth/FilmMagic/Getty Images; Courtesy of Disney; Walter McBride/WireImage/Getty Images]

 

Walt Disney Studios is developing a feature project based on the true-life story of an illegal immigrant from Mexico who became the current head of brain tumor surgery at John Hopkins Hospital.

Plan B, the production company run by Brad Pitt, Dede Gardner and Jeremy Kleiner, is producing the project, known as Dr. Q. Matt Lopez, the playwright behind the acclaimed Civil War drama The Whipping Man, is set to pen the screenplay.

Alfredo Quinones-Hinojosa crossed the border from Mexico when he was 19, living illegally in the country as he worked on farms in California. He saved up for English classes and then saved up to attend school. He showed a propensity for the medical arts and attended Harvard Medical School. He became a celebrated brain surgeon and cancer researcher, penning cover stories in the fields of science and medicine while also being a cover subject. He is the director of brain tumor surgery at the John Hopkins Hospital.

Plan B’s relationship with Quinones-Hinojosa began in 2007 after execs first heard his story on a radio program.

Disney sees Dr. Q being a modestly budgeted inspirational drama, in the mold of its recently wrapped movie Queen of Katwe — an inspirational true story of a young Ugandan girl who becomes a chess champion — starring Lupita Nyong’o and David Oyelowo.

More at HollyWoodReporter.com

Bring the Kiddos to Meet a Real Life ‘Superhero’

 

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Come dressed as your favorite superhero and enjoy a fun-filled afternoon with music, games, prizes, food, and entertainment.

Meet real life superheroes such as firefighters, emergency medical personnel, police officers, military service members, and the Memorial Hermann Life Flight® team at Pearland’s Memorial Hermann Convenient Care Center’s free ‘Superhero’ Day on Saturday, Nov. 8, 11 a.m. – 2 p.m.

Kids of all ages are encouraged to come dressed as their favorite superheroes and hang out with Children’s Memorial Hermann giraffe mascot Topper, H-E-Buddy, and many other characters. Enjoy a fun-filled afternoon with music, games, prizes, food, entertainment, and special performances by Precision Dance Academy.

 

Cohosted by H-E-B Plus and the YMCA, admission is free and the event is open to the entire community.

 

WHEN:         Saturday, Nov. 8, 11 a.m. – 2 p.m.

                 

WHERE:      Memorial Hermann Convenient Care Center in Pearland

                        10905 Memorial Hermann Dr., Pearland, TX 77584

 [Photo Courtesy of GalleryHip.com]

Findings Give Hope to Plant Extract as Possible #Lupus Treatment

New findings by a biomedical engineer and his team at the University of Houston (UH) raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks and side effects often associated with current treatments for this disease.

Lupus, or systemic lupus erythematosus, is a progressive, degenerative disease in which the immune system turns against itself, attacking a person’s healthy tissue, cells and organs. Symptoms range from debilitating pain and fatigue to organ failure and a host of other impairments. An estimated 1.5 million Americans, and at least five million people worldwide, have a form of lupus.

Though there is no cure, a UH researcher and his team are actively working toward finding new treatments and, ultimately, a cure. Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed Professor of biomedical engineering in the UH Cullen College of Engineering, and his group’s latest work could lead to new, more natural therapeutics for lupus that use a plant-derived chemical. The promising findings were recently published in Arthritis & Rheumatology, the monthly journal of the American College of Rheumatology.

With only one drug specifically approved for the treatment of lupus in the past 50 years, lupus patients are commonly treated with steroids, a class of immunosuppressive drugs that delay the development and progression of the disease by suppressing the immune system. By suppressing the immune system in its entirety, however, this mode of treatment carries with it an increased risk of infections and other harmful side effects.

In this latest research, Mohan and his colleagues present new findings that detail the use of a synthetic, plant-derived compound – abbreviated CDDO – that was shown to effectively suppress the multiple steps of lupus development in murine models, including the onset of kidney disease.

One of the most common organs to be attacked by lupus is the kidney, manifesting in lupus nephritis. While this condition doesn’t affect all lupus sufferers, an estimated 40 percent of lupus patients develop it. Lupus nephritis, which causes inflammation of the kidneys and impairs their ability to effectively rid the body of waste products and other toxins, is the leading cause of lupus-related deaths and results in tens of thousands of hospitalizations per year.

“The development of lupus is a two-step reaction. First, the immune system develops antibodies that attack the body’s own DNA, then that activated immune system attacks the kidneys,” Mohan said. “We found that CDDO may block both of these steps.”

Mohan says there is much left to be discovered about CDDO, including how it works in suppressing the progression of lupus. The next step for this research is to confirm whether the CDDO compound suppresses the immune system across the board, or whether it simply suppresses the activation of the specific signaling pathways that lead to the development of lupus. To find this out, Mohan’s group will test it in the lab to see if they can mount the proper immune response. If not, Mohan says the compound likely could be suppressing the entire immune system, which is the current problem with using steroids to treat lupus. Even if the compound is shown to be generally immunosuppressive, however, it still may be a better treatment option than steroids for some patients.

 

More at www.uh.edu

[Recap] #LupusChat with Dr Akerkar on Lupus & Pregnancy

First, a huge thanks to Tiffany (@TiffanyandLupus) and Dr. Shashank Akerkar for the invaluable information. 

Secondly, no I am not pregnant.  I have Lupus and want to share this information with any of my fellow spoonies out there either already pregnant or thinking about starting a family. 

Here is some information that was shared yesterday.  However, I do recommend that you speak with your primary care physician on this matter.

1) Lupus does NOT make is harder to conceive.

2) However, data shows that spontaneous abortions and stillbirths 5 times risk as compared to non lupus pregnancies

3)Fetal loss in decreased from from 40% in 1960–65 to 17% 2000–03.

4) Lupus is not associated with infertility unless the woman has been treated with cyclophosphamide

5) Cyclophosphamide used for nephritis can lead to premature ovarian failure

6) Recent studies a higher incidence of premature menoapuse in #lupus probably due to anti ovary antibodies (Read more here)

7) One should not have active kidney disease (minimum 6 months) prior to planning pregnancy

For more information, visit TiffanyandLupus